About a case: affective psychosis and hyperthyroidism

Introduction Hyperthyroidism due to Graves-Basedow disease is a common cause of neuropsychiatric manifestations, such as anxiety, psychomotor restlessness, mood disturbances, insomnia and psychosis. Hashimoto’s encephalopathy rarely occurs in so-called autoimmune thyroiditis, which can present with hyperthyroidism symptoms similar Graves’ disease. We add that the mystical-religious beliefs, all human cultures, decisive case at hand, make us propose an evolutionary origin them. Objectives Clinical description Methods A clinical based on medical reports described Results 72-year-old woman, member Seventh-day Adventist Church, well adapted Community. Known history elevated antithyroid antibodies since 2019, brought emergency room involuntarily delusional condition associated behavioral disturbance. On examination, cachectic appearance, distal tremor, emotional exaltation megalomanic speech were highlighted. Laboratory tests revealed primary antibodies. During admission, differential diagnosis between was considered. Thyroid scintigraphy oriented disease, not requiring lumbar puncture or corticosteroid treatment. Treatment high-dose antipsychotic drugs, analytical remission 3 weeks. The patient referred Social Health Center for functional recovery. family refers episode 2014, less intensity self-limited, proposed be hashitoxicosis. Conclusions Differential Hashimoto essential they differ treatment prognosis. continuity delusion presents previous beliefs patient, differing mainly affective-behavioral implication, makes consider predisposition psychosis our patient. Religiosity adaptive certain environments, mystical have existed throughout species seem part nature. Disclosure Interest None Declared